Uterine and Endometrial Cancer Types

About 95% of uterine cancers are adenocarcinomas; endometrioid cancer is the most common type of adenocarcinoma. There are many sub-types of endometrioid cancers, including:

• Adenocarcinoma

• Adenocanthoma

• Adenosquamous

• Secretory carcinoma

• Ciliated carcinoma

• Villoglandular adenocarcinoma

• Uterine carcinosarcoma 

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Uterine sarcomas make up about 3% of uterine cancers. This type of cancer is rare and starts in the muscle and supporting tissues of the uterus. Most uterine sarcomas are put into categories depending on the type of cell they start in. 

• Uterine leiomyosarcoma - most common type. They start in the muscular wall of the uterus, also known as the myometruim, and grow and spread quickly.

• Endometrial stromal sarcoma - these are rare and start in the supporting connective tissue of the endometrium.

• Undifferentiated sarcoma - these cancers start either in the endometrium or myometrium, grow and spread quickly.

• PEComa is a malignant perivascular epithelioid cell tumor. Very rare!